What Is Protein In The Urine An Indication Of

How Is The Test Used

Urine Analysis: Protein

Urine protein testing is used to detect excess protein in the urine . A semi-quantitative test such as a dipstick urine protein may be used to screen for the presence of protein in the urine as part of a routine urinalysis.

A urine protein test may be used to screen for, help evaluate, and monitor kidney function and to help detect and diagnose early kidney damage and/or disease. However, the test can also help screen for several other conditions that can cause proteinuria.

If slight to moderate amounts of protein are detected, then a repeat urinalysis and dipstick protein may be performed at a later time to see if there is still protein in the urine or if it has become undetectable.

If there is a large amount of protein in the first sample, repeat testing will be ordered. If increased levels of urine protein are observed in follow-up specimens, then a 24-hour urine protein may be ordered along with certain blood tests. Since the dipstick method primarily measures the protein albumin, and if follow-up, repeat urine samples are positive, a 24-hour urine test also may be ordered to obtain more detailed information.

Either a 24-hour urine protein or a random protein to creatinine ratio may be used to monitor a person with known kidney disease or damage. A dipstick urine protein and/or a protein to creatinine ratio may be used to screen people on a regular basis when they are taking a medication that may affect their kidney function.

How Do I Get Ready For This Test

You may need to skip exercising for a certain time before the test. Let your healthcare provider know if you have a fever or have been ill recently.

Your provider will tell you if you should not take certain medicines on the day of the test. In addition, be sure your provider knows about all medicines, herbs, vitamins, and supplements you are taking. This includes medicines that don’t need a prescription and any illegal drugs you may use.

How Can You Tell If There Is Protein In Your Urine

If you have kidney damage and protein is escaping into your urine, you may notice the following symptoms:

  • Swelling in your face, abdomen or hands and feet.
  • Urine that appears bubbly, foamy or frothy.

If you notice either of these symptoms, talk to your doctor about the cause and what the best treatment may be. In some cases, the issue will resolve on its own without further treatment.

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Testing For Protein In Urine

The only way to diagnose proteinuria is through a urine test, which measures the amount of protein in your urine.

The test takes place in a doctors office. During the procedure, you urinate into a specimen cup. The doctor places a dipstick, or a small plastic stick coated with chemicals, into the urine sample. If it has too much protein, the stick will change color.

The rest of the urine will be sent to a lab, where its examined under a microscope.

If your doctor thinks you have kidney issues, theyll repeat the urine test three times in three months. This helps them rule out temporary causes of proteinuria.

A doctor might also use the following tests to determine whats causing your proteinuria:

  • 24-hour urine collection. In a 24-hour urine test, your urine is collected over 24 hours and sent to a lab.
  • Glomerular filtrate rate blood test. This test checks your kidney function.
  • Imaging tests. You may get an ultrasound or CT scan, which take detailed photos of your kidneys and urinary tract.
  • Kidney biopsy. A sample of your kidney is removed and examined for signs of kidney damage.

If you have temporary or mild proteinuria, you likely wont need treatment. But if you have consistent proteinuria, youll need to treat the underlying condition.

Treatment may include:

How Is Proteinuria Diagnosed

Urine Analysis: Part 12  Urine Albumin (24 hrs) or (24 ...

Proteinuria is diagnosed through a urine test. The patient provides a urine sample, which is examined in a lab. Doctors use a dipstick a thin plastic stick with chemicals on the tip to test part of the sample right away. If too much of any substance is in the urine, the chemical tip changes color.

The remainder of the urine is then examined under a microscope. Doctors look for substances that dont belong in urine. These substances include red and white blood cells, bacteria and crystals that can grow and develop into kidney stones.

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Who Is At Risk For Nephrotic Syndrome

Anyone can get nephrotic syndrome but it is slightly more common in men than in women. In children, it happens most often between the ages of 2 and 6. There are other factors that may increase your risk. You are more likely to get nephrotic syndrome if you:

  • Have a disease that affects the kidneys such as FSGS, lupus, or diabetes
  • Take certain medicines like nonsteroidal anti-inflammatory drugs or antibiotics
  • Have an infection such as HIV, hepatitis B and C, or malaria

Preeclampsia: When To Worry

If a patient has high blood pressure but no elevated protein levels, then they’re in gestational hypertension territory. When high blood pressure and high protein in the urine occur together in pregnancy, preeclampsia is a concern.;

Preeclampsia can be dangerous if it progresses. When accompanied by severe complications, hospitalization may be required and an early delivery scheduled. If you experience high blood pressure in your pregnancy , you should expect increased monitoring and more frequent doctor’s visits.

If you have preeclampsia, you’ll probably have a conversation with your doctor about a delivery at 37 weeks, Dr. Abernathy said. That’s the point at which there tends to be very few complications from delivery for the baby. Therefore, it’s better not to risk the mother’s health by continuing to wait.

While preeclampsia has historically been a driver of bad maternal health outcomes, doctors now are “very vigilant about it and we try to diagnose it early,” says Dr. Abernathy.;

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Protein In Urine During Pregnancy: What It Means And When To Worry

Some people experience high protein in urine during pregnancy. When it’s accompanied by high blood pressure, it’s likely a sign of preeclampsia. Here’s what expectant parents need to know.

Pregnancy is a time of increased doctor’s visits and close scrutiny of one’s health. There may also be a lot of tests that you haven’t encountered before, especially if your pregnancy is complicated.;

One screening that might be ordered is a test for the amount of protein in a pregnant person’s urine. There are several ways protein in urine in pregnancy might be tested, and we’ll break down what causes protein in urine, what a result of high protein in urine during pregnancy means, why these tests might be ordered, and importantly, when to worry.;

Can You Reduce Protein In Urine During Pregnancy

URINE ANALYSIS: Presence of PROTEIN in urine

Since high protein in urine is an indicator of other problems, it’s not something that’s usually treated directly, though it may be monitored after delivery if a doctor suspects a cause other than pregnancy. There’s no real way to reduce protein in urine in pregnancy, Dr. Abernathy said. Instead, it would be monitored along the guidelines laid out above and delivery would be considered if preeclampsia develops.;

It’s important to remember that preeclampsia is in many ways the luck of the draw. There’s not much a pregnant person can do to really prevent the condition , Dr. Abernathy said. If you have a history of high blood pressure, your doctor might recommend taking a baby aspirin, which has been shown to be beneficial for people at an elevated risk of developing preeclampsia.;

“So many people who have preeclampsia just are prone to developing hypertension and they’re going to have high blood pressure issues when they’re older,” she says.

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New Jersey Kidney Treatments & Diagnostics

Your kidneys are responsible for filtering out waste in your blood so that nutrients can perform their function in the body without contamination. Trace amounts of protein in urine is normal, but it should mostly be protein-free. High protein in urine is called proteinuria. This condition can cause a protein deficiency and could be an early warning sign of kidney disease.

How Will I Know If I Have Protein In My Urine

The only way to know if you have protein in your urine is to have a urine test. The test will measure the levels of protein in your urine.The name of the urine test that measures the level of albumin in your urine is called the urine albumin-to-creatinine ratio . A UACR compares the level of albumin to the level of creatinine . A normal UACR is less than 30mg/g. If your UACR is 30 mg/g or higher, it can be a sign of kidney disease, and you should ask your doctor if you should have other tests for kidney disease.

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What Other Tests Might I Have Along With This Test

You may also have a urine albumin-to-creatinine ratio test. This measures the ratio of protein to waste in your urine. You may have an ultrasound of your kidneys. And you may have blood tests, such as antinuclear antibody or complement. These are done to check for conditions that cause kidney problems.

When Is It Ordered

Urine Part 14:

A dipstick urine protein is measured frequently as a screening test whenever a urinalysis is performed. This may be done as part of a routine physical, a pregnancy workup, when a urinary tract infection is suspected, as part of a hospital admission, or whenever a healthcare practitioner wants to evaluate kidney function. Repeat testing may also be done when a previous dipstick has been positive for protein to see if the protein persists.

Specifically for monitoring people with possible kidney dysfunction, the National Kidney Foundation has established a 5-step plan for chronic kidney disease evaluation and referral using random urine albumin-to-creatinine ratio , rather than random UPCR, to screen for and determine the prognosis of CKD, for urine protein is more difficult to standardize.

A 24-hour urine protein may be ordered as a follow-up test, especially in pregnant women with a high pre-screen risk of preeclampsia, when the dipstick test shows that there is a large quantity of protein present in the urine or when protein is shown to be persistently present.

Since the dipstick primarily measures albumin, the healthcare practitioner may order a 24-hour urine protein test even when there is little protein detected on the dipstick if the practitioner suspects that there may be proteins other than albumin being released.

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What If My Kidneys Fail

If your kidneys stop working because of nephrotic syndrome, you will need dialysis or a kidney transplant to live. If you are interested in getting a transplant, you must have a full health evaluation by a transplant team at a transplant center. The evaluation will help the transplant team decide if you are ready for the kidney transplant. If the transplant team decides you are ready, the next step will be for your transplant team to help you find a kidney match. Learn more about the evaluation process and finding a match.

Is There Anything Else I Should Know

The different methods of detecting protein in the urine vary in performance. For example, a positive dipstick protein may be elevated due to other sources of protein, such as blood, semen, or vaginal secretions in the urine. Since it measures primarily albumin, the dipstick may occasionally be normal when significant quantities of other proteins are present in the urine.

A 24-hour urine sample gives the protein elimination rate over 24 hours. It will be accurate only if all of the urine is collected. The protein to creatinine ratio is more of a snapshot of how much protein is in the urine at the time the sample is collected. If it is elevated, then protein is present; if it is negative, the amounts or the type of protein released in urine may not be detectable at that time.

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How Often Do I Need To Have A Test For Albuminuria

People who are at increased risk for kidney disease should have this test as part of routine checkups by a healthcare provider.; Those at increased risk include:

  • People with diabetes

  • People with high blood pressure

  • People with a family history of kidney failure

  • People who are 65 years or older

  • Certain ethnic groups including African Americans, Hispanics, Asians, American Indians

Who Should Be Tested For Protein In The Urine

Protein in Urine (Proteinuria) | Causes and Symptoms | Urinox-10

If you are part of a group that is considered high risk for kidney disease, your doctor will test your urine for protein as part of your regular preventative care. People who are at risk for kidney disease include:

  • Those who are 65 or older.
  • Those who have a family history of kidney disease.
  • Those who have high blood pressure or diabetes.
  • Members of certain ethnic groups, including Hispanics, Native Americans, Asians and African Americans.

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How Is Nephrotic Syndrome Treated

There is no cure for nephrotic syndrome, but your doctor might tell you to take certain medicines to treat the symptoms. and to keep the damage to your kidneys from getting worse.

  • Medicine to control blood pressure and cholesterol can help prevent you from having a heart attack or a stroke.
  • Medicine to help your body get rid of extra water can help control your blood pressure and can reduce swelling.
  • Abnormally High Level Of Protein In The Urine Could Indicate Kidney Disease

    Proteinuria could indicate CKD. Where does protein in the urine come from? The protein is there in the blood. It exists as different types . Your muscles are primarily made of protein. The antibodies that circulate in your system fighting infection are protein. Hence protein is essential, but you normally shouldn’t be peeing it out into the urine.

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    What Is The Treatment For Proteinuria

    If you are diagnosed with kidney disease or your kidney functioning is declining, you will be referred by your doctor to a nephrologist, a doctor specializing in diseases of the kidneys. He or she will recommend treatment, which can include medication and changes in your diet and lifestyle. ;Treatment is tailored depending on what medical conditions are contributing to the proteinuria.

    How Is The Sample Collected For Testing

    17 Best images about Protein in Urine on Pinterest ...

    One to two ounces of urine is collected in a clean container. A sufficient sample is required for accurate results.

    Urine for a urinalysis can be collected at any time. In some cases, a first morning sample may be requested because it is more concentrated and more likely to detect abnormalities.

    Sometimes, you may be asked to collect a clean-catch urine sample. For this, it is important to clean the genital area before collecting the urine. Bacteria and cells from the surrounding skin can contaminate the sample and interfere with the interpretation of test results. With women, menstrual blood and vaginal secretions can also be a source of contamination. Women should spread the labia of the vagina and clean from front to back; men should wipe the tip of the penis. Start to urinate, let some urine fall into the toilet, then collect one to two ounces of urine in the container provided, then void the rest into the toilet.

    A urine sample will only be useful for a urinalysis if taken to the healthcare providers office or laboratory for processing within a short period of time. If it will be longer than an hour between collection and transport time, then the urine should be refrigerated or a preservative may be added.

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    When To Get Tested

    As part of a routine physical, often as part of a urinalysis; urine total protein and urine protein to creatinine ratio have traditionally been used as important indicators of kidney disease;and as a follow-up testing for monitoring the disease. However, albumin to creatinine ratio is now the preferred testing for these purposes.

    UPCR;should still be requested to identify preeclampsia in pregnant women and where the excess urine total protein is suspected to be other than albumin.

    Is There A Special Diet For Nephrotic Syndrome

    Changing how you eat may also help you manage your symptoms. When you have nephrotic syndrome, a dietitian may recommend you make changes to the amount of protein, salt, and fat that you eat. Check out Kidney Kitchen to learn more about how these nutrients can affect your kidneys.


    The amount of protein you should eat depends on how healthy your kidneys are. For some people with nephrotic syndrome, eating less protein is best. Talk to a dietitian about how much protein you should eat.


    Limiting how much salt you eat and drink can help prevent swelling and keep your blood pressure at a healthy level.

    Watch our video to get tips on managing sodium.

    Eating foods low in saturated fat and cholesterol can help prevent high cholesterol associated with nephrotic syndrome. Choosing fish or low-fat cuts of meat instead of cuts with high fat can help keep your cholesterol under control.

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    How Is A Urine Test Done

    A simple urine test can be done in your doctor’s office.; You will be asked to pee into a clean cup called a specimen cup.; Only a small amount of your urine is needed to do the test.; Some of the urine is tested right away with a dipstick a thin, plastic strip that is placed in the urine.; The rest is examined under a microscope.;

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