What Causes High Levels Of Protein In Urine

Is There Anything Else I Should Know

Can TOO MUCH Protein Cause High Urinary Sulfate Levels?

The different methods of detecting protein in the urine vary in performance. For example, a positive dipstick protein may be elevated due to other sources of protein, such as blood, semen, or vaginal secretions in the urine. Since it measures primarily albumin, the dipstick may occasionally be normal when significant quantities of other proteins are present in the urine.

A 24-hour urine sample gives the protein elimination rate over 24 hours. It will be accurate only if all of the urine is collected. The protein to creatinine ratio is more of a snapshot of how much protein is in the urine at the time the sample is collected. If it is elevated, then protein is present; if it is negative, the amounts or the type of protein released in urine may not be detectable at that time.

Too Much Protein In Urine What Causes It And How To Treat It

What does protein in urine mean? Is it dangerous to have elevated protein levels in the urine? Learn all about this condition and see how to treat it!

Not always the presence of protein in the urine means that there is a health problem, strictly speaking. Sometimes this depends on circumstances. But if this condition persists, it means that there is a difficulty in the functioning of the kidneys.

Proteins in urine are sometimes a sign that the kidneys are not working as well as they should. In principle, this condition does not generate any symptoms and is only detectable by a urine test. Therefore, most of the time it goes unnoticed in the initial phases.

We all have proteins in the blood. These play a very important role in the body, since they help to configure the bones and muscles, as well as to control the amount of fluids in the blood and to prevent infections, among others. However, these do not have to pass into the urine.

When there is protein in the urine, abundantly and persistently, it means that the kidneys are making an incorrect filter. They should process and dispose of waste and not proteins. It is an early sign of kidney problems, which you should address immediately.

When Is It Ordered

A dipstick urine protein is measured frequently as a screening test whenever a urinalysis is performed. This may be done as part of a routine physical, a pregnancy workup, when a urinary tract infection is suspected, as part of a hospital admission, or whenever a healthcare practitioner wants to evaluate kidney function. Repeat testing may also be done when a previous dipstick has been positive for protein to see if the protein persists.

Specifically for monitoring people with possible kidney dysfunction, the National Kidney Foundation has established a 5-step plan for chronic kidney disease evaluation and referral using random urine albumin-to-creatinine ratio , rather than random UPCR, to screen for and determine the prognosis of CKD, for urine protein is more difficult to standardize.

A 24-hour urine protein may be ordered as a follow-up test, especially in pregnant women with a high pre-screen risk of preeclampsia, when the dipstick test shows that there is a large quantity of protein present in the urine or when protein is shown to be persistently present.

Since the dipstick primarily measures albumin, the healthcare practitioner may order a 24-hour urine protein test even when there is little protein detected on the dipstick if the practitioner suspects that there may be proteins other than albumin being released.

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What Does Protein In The Urine Mean

Protein is normally found in your blood. The main protein in your blood is called albumin. Proteins have many important jobs in your body. For example, they help build your bones and muscles, prevent infection and control the amount of fluid in your blood.

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You Are Reading: Protein in Urine Causes, Symptoms, & Treatments

What Other Tests Might I Have Along With This Test

Urinalysis 3/27

You may also have a urine albumin-to-creatinine ratio test. This measures the ratio of protein to waste in your urine. You may have an ultrasound of your kidneys. And you may have blood tests, such as antinuclear antibody or complement. These are done to check for conditions that cause kidney problems.

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Diabetes and hypertension are the top causes of kidney disease, so if you have these conditions, your treatment will include getting these under control. ;For diabetics, this can include managing blood sugar, taking medication, eating healthy, and exercising.

For people with hypertension, doctors may recommend medication as well as diet and lifestyle changes. People with hypertension and proteinuria are also advised that they should keep their blood pressure below 130/80 millimeters of mercury .

People with diabetes and kidney disease or hypertension and kidney disease are often prescribed medications, including angiotensin-converting enzyme inhibitors or angiotensin receptor blockers . These medications may also be prescribed to people with kidney disease who do not have diabetes or hypertension.

If kidney damage is permanent, patients may also require dialysis or a kidney transplant.

Causes Of Protein In The Urine

Your kidneys, when working properly, filter waste products from your blood. They return protein and other materials that your body needs to function.

Some conditions and diseases can cause the level ofprotein in your urine to rise. Short term conditions that cause protein in the urine can include strenuous exercise, fever, heat or cold exposure and emotional distress.;Long term conditions and diseases that can lead to protein in the urine include high blood pressure, kidney infection or disease, heart disease, diabetes, lupus and malaria.If a urine test reveals protein in your urine, your doctor may recommendfurther testing to determine the cause. Test may include a 24-hour urine collection to determine whether the protein in your urine is cause for concern. Your doctor may also follow up with an ultrasound or CT scan to look for issues like kidney stones or a biopsy to see what has caused damage to your kidneys.

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What Happens When Chronic Kidney Disease Or Another Serious Condition Is Diagnosed Or Suspected

A doctor who suspects kidney disease would repeat the urine test three times over three months. If the samples test positive for proteins each time, the patient likely has kidney disease. The earlier the diagnosis, the more chance doctors have to slow the disease and stop it from progressing.

Additional tests might include:

Protein In Urine Symptoms

Protein in Urine Levels | Proteinuria Causes | Protein Loss in Urine | Protein in Urine Treatment

Most people who have proteinuria wonât notice any signs, especially in early or mild cases. Over time, as it gets worse, you might have symptoms including:

  • Foamy or bubbly pee
  • A family history of kidney disease
  • African American, Native American, Hispanic, or Pacific Islander descent

Some people get more protein into their urine while standing than while lying down. This condition is called orthostatic proteinuria.

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Why Is Finding Protein In My Pets Urine A Cause For Concern

Protein is a precious resource for the body, and the kidneys have an important role to prevent it from being lost in the urine. The presence of protein in urine is called proteinuria, and it may indicate that the kidneys are not working properly. In some situations, it may even be a sign of kidney failure.

Why Is Sugar In Urine

It’s normal and healthy for there to be glucose in the blood, and the normal range for blood glucose is around 70 mg/dL110 mg/dL, and it can fluctuate throughout the day. When your blood is filtered through the kidneys it carries with it the sugar that is normally in your bloodstream.

Your kidneys are then responsible for filtering blood by removing wastes and excess fluid and returning the cleaned blood back to the body, filtering the rest to the bladder to be excreted in your urine.

Most of the sugar is reabsorbed by the kidneys and put back into the bloodstream. However, some sugar remains and travels with the rest of the fluid to the bladder, leaving the body with your urine.

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Does Kidney Damage Go Away

In general, it does not. The goal is to detect kidney disease and damage early to minimize the damage and prolong kidney function. If the proteinuria detected is due to a kidney infection or urinary tract infection, the kidneys frequently will return to normal function as the infection resolves. If it is due to a medication, then in most cases the kidneys are likely to return to normal or near-normal function when the medication is stopped.

How Does Eating Diet And Nutrition Affect Nephrotic Syndrome

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Eating, diet, and nutrition have not been shown to play a role in causing or preventing nephrotic syndrome. However, if you have developed nephrotic syndrome, your health care professional may recommend that you

  • limit intake of sodium and fluids to help control swelling
  • reduce the amount of fat and cholesterol in your diet to help control your blood cholesterol levels

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How To Test Proteins In Urine

Make sure you inform your doctor about any medications that are being taken. Because some drugs can affect the level of protein in the urine.

Your doctor may ask you to stop taking certain medications or change the dosage before undergoing an examination.

There are 2 types of urine protein examination, namely random examination and urine test that comes out for 24 hours.

What Are Clinical Trials For Nephrotic Syndrome

Clinical trialsand other types of clinical studiesare part of medical research and involve people like you. When you volunteer to take part in a clinical study, you help doctors and researchers learn more about disease and improve health care for people in the future.

Researchers are studying many aspects of nephrotic syndrome, such as

  • the kidney diseases that can lead to nephrotic syndrome, including genes that may cause these diseases
  • quality of life among people with nephrotic syndrome
  • how to best treat nephrotic syndrome

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How Do I Get Ready For This Test

You may need to skip exercising for a certain time before the test. Let your healthcare provider know if you have a fever or have been ill recently.

Your provider will tell you if you should not take certain medicines on the day of the test. In addition, be sure your provider knows about all medicines, herbs, vitamins, and supplements you are taking. This includes medicines that don’t need a prescription and any illegal drugs you may use.

What Do My Test Results Mean

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Test results may vary depending on your age, gender, health history, the method used for the test, and other things. Your test results may not mean you have a problem. Ask your healthcare provider what your test results mean for you.

Results are given in milligrams .;Normal urine protein in adults is less than 150 mg within a 24-hour period.

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What If Proteinuria Is Present Without Inflammation Or Bleeding

If proteinuria is present and there is no sign of inflammation or bleeding, then serious kidney disease may exist. The best test to determine the severity of the problem is the urine protein:creatinine ratio . A protein:creatinine ratio that remains persistently high is a reliable indicator of serious kidney disease and possibly kidney failure. Further investigation is recommended and could include doing blood tests to assess kidney function, testing for bacterial infection or infectious disease, performing an ultrasound of the kidneys and possibly doing a kidney biopsy.;Once a diagnosis has been made, effective management of the problem may be possible.

Contributors: Malcolm Weir, DVM, MSc, MPH; Kristiina Ruotsalo, DVM, DVSc, Dip ACVP; Margo S. Tant BSc, DVM, DVSc

How Often Do I Need To Have A Test For Albuminuria

People who are at increased risk for kidney disease should have this test as part of routine checkups by a healthcare provider.; Those at increased risk include:

  • People with diabetes

  • People with high blood pressure

  • People with a family history of kidney failure

  • People who are 65 years or older

  • Certain ethnic groups including African Americans, Hispanics, Asians, American Indians

What Results Are Obtained From The Urine Protein Examination Procedure

Your doctor will check the protein levels in your urine sample. If the results show high levels of protein, you will be asked to undergo another urine protein test. Your doctor may also recommend physical examinations and laboratory tests.

High levels of protein in urine samples do not necessarily describe the presence of medical disorders that require treatment. Strenuous exercise, diet, stress, pregnancy, and some other factors can make high protein levels temporarily in urine.

However, if after undergoing some health courses, the protein levels in your urine remain high, this condition may indicate:

  • Urinary tract infections
  • Lupus disease
  • High blood pressure
  • Pre-eclampsia, as a serious complication during pregnancy, which can be life-threatening to both mother and baby
  • diabetes

Protein In Urine Diagnosis

Normal Protein Levels In Urine

A urine test called a urinalysis can tell whether you have too much protein in your pee. First, youâll pee into a cup. A lab technician will dip in a stick with chemicals on the end. If the stick changes color, itâs a sign of too much protein. You might need to have this test more than once to find out how long the protein is there.

The technician will also look at the pee under a microscope. Theyâre checking for things that shouldnât be there, which might mean kidney problems. These include red and white blood cells, crystals, and bacteria.

If your doctor suspects kidney disease, you might need to have other urine tests. Your doctor might also order:

  • Blood tests. These measure certain chemicals to check how well your kidneys are working.
  • Imaging tests. CT scans and ultrasounds can spot kidney stones, tumors, or other blockages.
  • A kidney biopsy. Your doctor might need to take a small sample of kidney tissue so a lab technician can look at it under a microscope.

Could Protein Drinks Cause High Protein Levels In Urine

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What Else Causes Protein In Urine

Proteinuria causes are linked to other conditions. Diabetes and high blood pressure are the two leading causes of chronic kidney disease , and kidney damage from those two conditions can result in proteinuria. Lupus, arthritis and other immune system disorders can also cause proteinuria. Protein in the urine can even be a warning sign of pre-eclampsia during pregnancy.

Protein In Urine Normal Range

The protein in urine normal range is calculated in milligrams per deciliter. Protein in urine normal range is set at 20 mg/dL as the upper limit. The sample for urinalysis is collected randomly or at a time agreed on with your doctor. For better diagnostics, a doctor may order samples to be collected over a period of a day for the 24-hour proteinuria test. The 24 hour urine protein normal range is 80mg/dl in the lower limit.

From random samples and simple testing, it is possible to tell if there are proteins in urine. Though it does not give accurate measurements of the levels of each protein type, the protein in urine 1+ reporting system for proteinuria tests is still in wide use.

There are two tests for identifying proteinuria. They are the 24-hour urine test and the Spot urinalysis. One collects samples over a period of 24 hours while the other utilizes a randomly collected sample. If a randomly collected sample shows a problem with the levels of protein in your urine, your doctor may want you to have the 24-hour urine test.

Results from testing for proteinuria are classified into 24-hour urine analysis results and spot urine results. A further reading centred on the ration of albumin to creatinine is made from analyzing your urine in the laboratory. The 24 hour urine protein creatinine ratio must not exceed 0.15.

How To Treat Proteinuria

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Being diagnosed with proteinuria is disheartening. It is however not life threatening. With proper management, proteinuria will go away. You will need to implement some lifestyle changes. These will include better diet management. You will also be asked to stop smoking, drinking alcohol, and lose excess weight.

Medication may be given in the course of treating your proteinuria. Only use drugs prescribed by your doctor and approved for treatment of proteinuria. Follow the dosage of such medication faithfully.

A number of health problems can lead to proteinuria. They include high blood pressure, infections, drugs, diabetes and mediation, tumors such as multiple myeloma and kidney disease, Mild proteinuria is not indicative of a serious disorder. Nevertheless, elevated amounts of protein in your urine are not considered normal. Persistently high protein levels in urine outside the protein in urine normal range is often a sign of improperly functioning kidneys.

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When To See A Doctor

If a urine test reveals protein in your urine, ask your doctor whether you need further testing. Because protein in urine can be temporary, your doctor might recommend a repeat test first thing in the morning or a few days later.

Your doctor might order other tests, such as a 24-hour urine collection, to determine if there is a cause for concern.

If you have diabetes, your doctor may check for small amounts of protein in urine also known as microalbuminuria once or twice each year. Newly developing or increasing amounts of protein in your urine may be the earliest sign of diabetic kidney damage.

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