What Are The Symptoms Of Nephrotic Syndrome
You may not know that you have nephrotic syndrome until you have routine blood and urine testsat a doctor’s appointment. The results of your tests can show that you have too much protein in your urine, not enough protein in your blood, or too much fat or cholesterol in your blood.Signs of nephrotic syndrome that you may notice are:
- Swelling in your legs, feet, ankles and sometimes face and hands
- Weight gain
- Not feeling hungry
Proteinuria : Symptoms & Signs
- Medical Author: Melissa Conrad Stöppler, MD
Medically Reviewed on 9/10/2019
Proteinuria refers to excess protein in the urine. While some amount of protein in the urine is normal, excessive amounts of protein in the urine are a sign that the kidneys are not working properly due to a number of different reasons. The main protein in the blood is albumin, and this is also the main protein in urine. For this reason, proteinuria is sometimes referred to as albuminuria. Diabetes and hypertension are two chronic conditions that can cause kidney damage over time, leading to excess protein in the urine. Acute problems with the kidneys, like acute renal failure, also cause proteinuria. Some conditions can transiently increase the amount of protein in the urine, including emotional stress, vigorous exercise, fever, or exposure to heat or cold extreme temperatures.
Other causes of proteinuria
What If Proteinuria Is Present Without Inflammation Or Bleeding
If proteinuria is present and there is no sign of inflammation or bleeding, then serious kidney disease may exist. The best test to determine the severity of the problem is the urine protein:creatinine ratio . A protein:creatinine ratio that remains persistently high is a reliable indicator of serious kidney disease and possibly kidney failure. Further investigation is recommended and could include doing blood tests to assess kidney function, testing for bacterial infection or infectious disease, performing an ultrasound of the kidneys and possibly doing a kidney biopsy. Once a diagnosis has been made, effective management of the problem may be possible.
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Tips To Get Rid Of Protein In Urine
In addition to using the right medications, how to get rid of protein in the urine is by following some tips, such as:
- Eat a healthy diet that is low in fat and low in salt .
- Limit protein intake.
- Reduce the amount of fluids you drink.
- Quit Smoking.
- Do not take non-steroidal anti-inflammatory drugs, such as: ibuprofen and naproxen, except after consulting a doctor.
- Consult your physician before taking any nutritional supplement or herbal.
- Excess weight loss.
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Diabetes and hypertension are the top causes of kidney disease, so if you have these conditions, your treatment will include getting these under control. For diabetics, this can include managing blood sugar, taking medication, eating healthy, and exercising.
For people with hypertension, doctors may recommend medication as well as diet and lifestyle changes. People with hypertension and proteinuria are also advised that they should keep their blood pressure below 130/80 millimeters of mercury .
People with diabetes and kidney disease or hypertension and kidney disease are often prescribed medications, including angiotensin-converting enzyme inhibitors or angiotensin receptor blockers . These medications may also be prescribed to people with kidney disease who do not have diabetes or hypertension.
If kidney damage is permanent, patients may also require dialysis or a kidney transplant.
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What Causes Kidneys To Leak Protein & How To Stop It
Does your urine appear frothy or slimy? It could be proteinuria. This occurs when kidneys are unable to filter protein, which then leaks out in the urine. Know what causes kidneys to leak protein and how to stop it.
Leakage of protein in urine via kidneys can not only change the appearance of urine but can also suggest presence of some chronic kidney disorder. Instead of ignoring it for long, get medical advice as early as possible to prevent worsening of the symptoms. But, before you visit the doctor, do understand about proteinuria and what can be done to cure it! Let us understand what causes kidneys to leak protein and ways to stop it.
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Pregnancy And Trace Ketones In Urine
If abnormal or trace ketones in urine occur during pregnancy then it could be an indication of gestational diabetes. This condition can be detrimental for the unborn child. Hence, pregnant women need to seek immediate medical attention if ketones in urine are detected.
It may also be noted that excessive vomiting and nausea which normally occurs during pregnancy can also lead to elimination of trace ketones in urine.
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Questions To Ask Your Doctor
If you find out you have nephrotic syndrome, talk with your doctor about the cause of your symptoms and what treatment is best for you. Here are some questions you may want to ask:
What If My Kidneys Fail
If your kidneys stop working because of nephrotic syndrome, you will need dialysis or a kidney transplant to live. If you are interested in getting a transplant, you must have a full health evaluation by a transplant team at a transplant center. The evaluation will help the transplant team decide if you are ready for the kidney transplant. If the transplant team decides you are ready, the next step will be for your transplant team to help you find a kidney match.
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How Is This Test Done
This test needs a 24-hour urine sample. For this sample, you must collect all of your urine for 24 hours. Empty your bladder completely first in the morning without collecting it. Note the time. Then collect your urine every time you go to the bathroom over the next 24 hours. You will collect it in a container that your healthcare provider or the lab gives you.
Whats Wrong With Having Albumin In My Urine
One of the main jobs of your kidneys is to filter your blood. When your kidneys are healthy, they keep important things your body needs inside your blood, like protein. They also remove things your body doesnt need, like waste products and extra water.
If your kidneys are damaged, protein can leak out of the kidneys into your urine. Having protein in your urine is called albuminuria or proteinuria.
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Proteinuria In Children Treatment
If tests show your child has orthostatic proteinuria or only small amounts of protein in his or her urine, no treatment is needed.
If tests show a large amount of protein in your childs urine, and he or she has swelling of the legs and eyelids, your doctor may send him or her to a kidney specialist. This doctor is called a nephrologist. The nephrologist may perform a kidney biopsy. During this simple surgical procedure, a small piece of kidney tissue is removed. Your doctor will look at the piece under a microscope. This may help him or her find out what is causing the protein in your childs urine. Once the doctor knows why its happening, he or she can treat the problem.
Diabetic Kidney Damage May Be Reversible
Diabetes is the most common cause of kidney failure. Until recently, it was thought that once a diabetic leaks protein into his urine, the kidneys are damaged and can never heal. However, kidneys damaged by diabetes have healed after high blood pressure has returned to normal and after pancreatic transplants. Blood pressure medications called Ace inhibitors and angiotensin receptor blockers have also healed diabetes-damaged kidneys. The kidney is supposed to allow urine, but not protein, to pass through its filters. Doctors used to tell diabetics that since damaged kidneys never heal, they could never take metformin, an important drug for treating diabetes. Now all diabetics should be told to get their diabetes under control by avoiding refined carbohydrate , losing weight, exercising, stopping smoking, and getting their HBA1C blood tests to normal. If their kidneys stop spilling protein, they may be able to take metformin again. 1) Remission and regression of diabetic nephropathy. Hypertension Research, 2003, Vol 26, Iss 7, pp 515-519. H Makino, Y Nakamura, J Wada. Makino H, Okayama Univ, Grad Sch Med & Dent, Dept Med & Clin Sci, 2-5-1 Shikata Cho, Okayama 7008558, JAPAN. 2) Regression of albuminuria: latest evidence for a new approach. Journal of Hypertension, 2003, Vol 21, Suppl. 3, pp S24-S28. G Viberti. Guys Kings & St Thomas Sch Med, Dept Diabet Endocrinol & Internal Med, Sch Med, London SE1 9RT, ENGLAND Checked 2/23/17Continue reading > >
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Causes Of High Protein
There may be various factors responsible for high protein amount in urine. Dehydration, high blood pressure, diabetes mellitus, glomerulonephritis, autoimmune problems, and chronic kidney disease, etc. Apart from that, many other factors such as intake of certain medicines, dehydration, and intense physical activities may be responsible for protein loss in urine. proteinuria treatment emphasises on managing its causative factors.
What Are The Signs Of Proteinuria And Kidney Failure
Large amounts of protein in your urine may cause it to look foamy in the toilet. Also, because the protein has left your body, your blood can no longer soak up enough fluid and you may notice swelling in your hands, feet, abdomen, or face. These are signs of very large protein loss. More commonly, you may have proteinuria without noticing any signs or symptoms. Testing is the only way to find out how much protein you have in your urine.
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What Are The Causes Of Pediatric Proteinuria
One of the functions of protein in the blood is to help balance the bodys fluid levels. When protein spills into the urine, it causes fluid to leak into the bodys tissues, which results in swelling.
Although proteinuria is often harmless and may result from stress, fever or exercise, it also can be a sign of a serious underlying kidney disease or a disease that started in another part of your childs body. Proteinuria also may be a sign of another condition, nephrotic syndrome, which may indicate an underlying kidney disease.The most common risk factors for proteinuria are diabetes and hypertension, or high blood pressure. Both of these diseases can cause kidney damage and proteinuria.
Risk factors include:
- Family history of kidney disease
- Kidney damage or disease
Tests For Kidney Disease
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The only way to know how well your kidneys are working is to get tested. Kidney disease often has no symptoms until your kidneys are badly damaged. Testing is especially important if you have diabetes, high blood pressure or a family history of kidney disease.
Ask your doctor about these kidney tests. Finding and treating kidney disease early can help you slow or stop damage to your kidneys.
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Why Do I Need This Test
If you are pregnant, you may have this test as a part of routine prenatal care to screen for preeclampsia.
You may also have this test if your healthcare provider thinks that you have protein in your urine. Proteinuria may not cause symptoms in the early stage. But as kidney function worsens, you may notice these symptoms:
Higher level of blood creatinine
You may also need this test if you:
Have a family member who has chronic kidney disease
Are at risk for kidney disease
Does Kidney Damage Go Away
In general, it does not. The goal is to detect kidney disease and damage early to minimize the damage and prolong kidney function. If the proteinuria detected is due to a kidney infection or urinary tract infection, the kidneys frequently will return to normal function as the infection resolves. If it is due to a medication, then in most cases the kidneys are likely to return to normal or near-normal function when the medication is stopped.
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Causes Of Protein In The Urine
Your kidneys, when working properly, filter waste products from your blood. They return protein and other materials that your body needs to function.
Some conditions and diseases can cause the level ofprotein in your urine to rise. Short term conditions that cause protein in the urine can include strenuous exercise, fever, heat or cold exposure and emotional distress. Long term conditions and diseases that can lead to protein in the urine include high blood pressure, kidney infection or disease, heart disease, diabetes, lupus and malaria.If a urine test reveals protein in your urine, your doctor may recommendfurther testing to determine the cause. Test may include a 24-hour urine collection to determine whether the protein in your urine is cause for concern. Your doctor may also follow up with an ultrasound or CT scan to look for issues like kidney stones or a biopsy to see what has caused damage to your kidneys.
Risk Factors For Proteinuria
Certain people are more likely to develop proteinuria. Common risk factors include:
- Age. Adults 65 and older are more susceptible to dehydration and kidney issues. Pregnant people older than 40 have a greater risk of preeclampsia.
- High blood pressure. People with high blood pressure have higher risk for diabetes and kidney disorders.
- Diabetes. Diabetes is the most common cause of CKD. Its also associated with preeclampsia and glomerulonephritis.
- Family history. Youre more likely to develop proteinuria if you have a family history of kidney disease or preeclampsia.
- Certain ethnicities. People of African American, Latino, American Indian, and Asian descent have a greater risk of kidney issues.
- Being overweight or obese. High blood pressure, diabetes, and preeclampsia are associated with being overweight or obese.
In the early stages of kidney damage, you wont have any symptoms. Thats because there are only small amounts of protein in your urine.
But as kidney damage progresses, more protein will pass into your urine. This may cause symptoms like:
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What Foods Can Cause Protein In Urine
However, you should avoid foods that are high in potassium and magnesium, if you are have been diagnosed with Proteinuria. Foods that are high in potassium include most fresh fruits and vegetables. Some specific examples include: Oranges and orange juice.
How Is Proteinuria Diagnosed
Proteinuria is diagnosed through a urine test. The patient provides a urine sample, which is examined in a lab. Doctors use a dipstick a thin plastic stick with chemicals on the tip to test part of the sample right away. If too much of any substance is in the urine, the chemical tip changes color.
The remainder of the urine is then examined under a microscope. Doctors look for substances that dont belong in urine. These substances include red and white blood cells, bacteria and crystals that can grow and develop into kidney stones.
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How Can I Prevent Diabetes From Causing Kidney Disease
Work with your doctor to create a plan to prevent or slow damage to your kidneys. Even if your kidneys are already damaged, you can slow the damage from getting worse. Your plan may include to:
- Work with your doctor to control your blood sugar. Tell your doctor if your blood sugar is often too high or too low.
- Work with your doctor to control your blood pressure. Having both diabetes and high blood pressure can make you more likely to get kidney disease.
- Work with your doctor to manage your cholesterol. Cholesterol is a waxy, fat-like substance in your blood. Having both diabetes and high cholesterol can make you more likely to get kidney disease. High cholesterol can also make your diabetic kidney disease get worse faster. Ask your doctor what your cholesterol level should be and how you can control it.
- Take all of your prescription medicines as your doctor tells you.
- Meet with a diabetes educator or dietitian to help you create and follow an eating plan.
- Quit smoking or using tobacco.
- Be active at least 30 minutes a day on most days of the week. Being active helps your body use insulin better.
- Stay at a healthy weight. Ask your doctor what a healthy weight is for you.
What Does Protein In The Urine Mean
Protein is normally found in your blood. The main protein in your blood is called albumin. Proteins have many important jobs in your body. For example, they help build your bones and muscles, prevent infection and control the amount of fluid in your blood.
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Which Protein Is Associated With Proteinuria
The blood has several protein components, out of which albumin is relevant among all. The albumin accounts for nearly 50% of the total serum proteins. It helps the body maintain fluid balance by preventing it from slipping into the cells and tissues. Often, this is a reason proteinuria patients tend to suffer high blood pressure than the general population. Sudden weight gain is yet another condition associated with proteinuria. It also does the following of the functions of our body:
- Acting as a transporting agent to provide important nutrients, such as bilirubin, fatty acids, metals, ions, hormones to the body.
- Helps maintain bone and muscle.