What Causes Kidneys To Leak Protein
Proteins are building blocks of life. Albumin is the main protein found in human blood. Proteins are responsible for a diverse range of functions, right from helping in cell and muscle growth to controlling fluid in blood they also help in preventing infection and diseases.
We have a pair of kidneys in our body that act as blood filters. It is the function of the kidneys to let the nutrients and proteins pass while returning them back to the blood stream. However, in case of any malfunction of kidneys, some amount of protein could leak into urine leading to a condition called proteinuria. Thus, any disorder affecting the kidneys, causes kidneys to leak protein.
Protein can be released from the kidneys in large as well small quantities. Sometimes, it can even go unnoticed for a long period of time in the absence of symptoms. There can be many causes for protein leakage which can range from non-malignant to extremely lethal.
While, healthy kidneys are responsible for flushing out water and fluid from the blood making it clean to flow in the system, any kind of malfunction can pose problems in this task. Protein which should ideally be retained, gets leaked and comes out in urine in case of proteinuria.
Here are some of the commonest conditions that causes kidneys to leak protein:
- Heart Failure
- Complications of other conditions like diabetes, affecting the kidneys, as in diabetic nephropathy.
How Can You Tell If There Is Protein In Your Urine
If you have kidney damage and protein is escaping into your urine, you may notice the following symptoms:
- Swelling in your face, abdomen or hands and feet.
- Urine that appears bubbly, foamy or frothy.
If you notice either of these symptoms, talk to your doctor about the cause and what the best treatment may be. In some cases, the issue will resolve on its own without further treatment.
How Does Eating Diet And Nutrition Affect Nephrotic Syndrome
Eating, diet, and nutrition have not been shown to play a role in causing or preventing nephrotic syndrome. However, if you have developed nephrotic syndrome, your health care professional may recommend that you
- limit intake of sodium and fluids to help control swelling
- reduce the amount of fat and cholesterol in your diet to help control your blood cholesterol levels
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How To Get Rid Of Protein In Urine
Protein in urine is not a condition to consider lightly. If you detect it early you can save yourself from kidney disease.
The condition is called proteinuria in which your kidney is not able to filter proteins efficiently so some proteins are excreted with urine.
There are no symptoms in the early stages of proteinuria but in advance stages you can see bubbly frothy urine in the toilet.
High blood pressure and diabetes are the main causes. You can get rid of proteins in urine with the same home remedies that are good for hypertension and diabetes type 2.
Protein in urine is not a disease itself but is an indication of kidney disease. A protein called albumin increases in the urine.
Main causes of protein in urine are high blood pressure and kidney diseases. So if you have diabetes and high blood pressure both then you are likely to get Proteinuria at some stage when your kidney gets affected.
High blood pressure and diabetes type 2 are generally lifestyle disorders. It is important that both these conditions are kept in check to not only prevent Proteinuria but also many other health conditions.
In addition to these certain medications, infections and trauma can increase proteins in your urine. Some autoimmune conditions can also cause the same harm.
Initially there are no symptoms. When your kidney get damaged and amount of protein significantly increase in your urine, you will notice the following symptoms:
Does Kidney Damage Go Away
In general, it does not. The goal is to detect kidney disease and damage early to minimize the damage and prolong kidney function. If the proteinuria detected is due to a kidney infection or urinary tract infection, the kidneys frequently will return to normal function as the infection resolves. If it is due to a medication, then in most cases the kidneys are likely to return to normal or near-normal function when the medication is stopped.
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High Protein In Urine
Your kidneys serve, in part, to remove any waste or excess fluid from your blood, while allowing important things like proteins to remain. Healthy kidneys are really good at this job, but if you have an underlying disease or condition that affects your kidney function, proteins can pass through the filtering mechanisms in your kidneys and land in your urine. This is called proteinuria .
There are lots of different conditions that can cause proteinuria, but some of these include:
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Is A Low Protein Diet The Answer
Even though it makes intuitive sense, and even though excess protein in the urine is directly associated with hyperfiltration, at this time the effect of protein restriction on renal function is uncertain. For now, suffice it to say that a moderate protein diet with about 0.8 grams per kilo body weight of protein per day, might be beneficial but going on a low protein diet may not be of benefit.
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Whats The Role Of Protein In The Body
Protein is an essential part of the normal body functioning including:
maintaining electrolytes level in the body
helping information of body tissues
providing energy to the body
triggering the development of immunoglobulin in the body
This protein present in the blood also helps in circulation of the essential nutrients throughout the body by binding them together.
Soy For Proteinuria Diet
Soy protein may offer numerous benefits for damaged kidneys. Animal proteins are high quality but hard on the kidneys and you may need to limit them in your diet. Vegetable proteins are less taxing and soy fits the bill as a high-quality vegetable protein. It might also help reduce proteinuria, according to a study published in 2003 in “Kidney International” which had patients follow a commonly recommended renal diet consisting of 70 percent animal protein and 30 percent plant protein followed by a diet consisting of 35 percent soy protein and 30 percent other vegetable proteins. Researchers found the addition of soy to the diet appeared to reduce proteinuria and improve renal function overall. However, you’ll need to choose the right soy products, according to registered dietitian Joan Brookshyer, writing for the American Association of Kidney Patients, who notes that many soy-based meat and cheese substitutes can be high in sodium, another nutrient you may need to limit in your diet. Read packages carefully.
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Treating Symptoms And Complications
Treatment varies according to symptoms, causes, and the extent of kidney damage. Symptoms of nephrotic syndrome are most often treated with these medicines3
- an angiotensin-converting enzyme inhibitor or an angiotensin II receptor blocker . ACEs and ARBs can help reduce protein loss and also lower blood pressure, which is often high in people with nephrotic syndrome.
- a diuretic , which reduces swelling by helping the kidneys remove fluid from the blood.
People with nephrotic syndrome should receive the pneumococcal vaccine, along with yearly flu shots, to prevent viral and bacterial infections.
How Do You Treat Excess Protein In The Urine
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|Image courtesy of Witthaya Phonsawat/ FreeDigitalPhotos.net|
A NOTE ABOUT SALT INTAKE SHOULD YOU RESTRICT YOUR PROTEIN INTAKE?mightWHAT IF YOU DON’T HAVE HIGH BLOOD PRESSURE ?even if they don’t have high blood pressure
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Change Your Protein Intake
Just because there are high protein levels in urine you don’t have to give up proteins all together.
However, lowering the consumption of proteins and changing to Healthy of proteins will make a significant improvement in your urine proteins.
Avoid red meats and move to lean proteins like chicken meat. Eat more fishes and soy proteins.
Soy proteins are light on kidneys as compared to animal proteins.
Since high blood pressure and diabetes are the main causes of rise if proteins in urine, fix these and you will get rid of proteinuria. Take following precautions.
- Lead a healthy life by exercising and sleeping well
- Reduce stress by deep breathing and meditation
- Drink lots of water throughout the day
- Avoid refined carbohydrates and sugar
- Stop alcohol and sugary colas and sodas
You are lucky if you identify proteins in urine early and take preventative action. Urine test every year if you are above 60 can save you from.kidney disease.
What Do The Results Mean
If a large amount of protein is found in your urine sample, it doesn’t necessarily mean that you have a medical problem needing treatment. Strenuous exercise, diet, stress, pregnancy, and other factors can cause a temporary rise in urine protein levels. Your health care provider may recommend additional urinalysis tests if a high level of protein is found This testing may include a 24-hour urine sample test.
If your urine protein levels are consistently high, it may indicate kidney damage or other medical condition. These include:
Learn more about laboratory tests, reference ranges, and understanding results.
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What Do They Look For In A Protein Test
One of the main proteins your healthcare provider looks for in this test is albumin. What is a urine protein test? A urine protein test is a screening test to look for the presence of proteins in the urine. One of these proteins is called albumin. Cleveland Clinic is a non-profit academic medical center.
How To Stop Kidneys From Leaking Protein
The first step to stop kidneys from leaking protein is to know the symptoms of it. Protein leak from kidneys is usually an indication of an underlying disease that needs to be diagnosed.
Leakage of large amounts of protein in the urine could be noticed with the following symptoms:
- Slummy, bubbling and frothy urine while using the toilet
- Body swelling around hands, feet, face and abdomen
- Sugar presence in urine in patients who have diabetes
- Weight gain due to fluid accumulation in the body
- Appetite gets reduced
- Protein supplements in blood are decreased. These include globulin and albumin.
While in most cases, proteinuria is detected with a urine examination done in patients suffering from high blood pressure or diabetes. If you notice the above symptoms, a urine examination if often advised for confirmation.
A urine examination would directly detect the presence of protein helping to identify proteinuria. The patient can get it done either at the doctorâs clinic or a pathology centre. The patient would be asked to give the urine sample in a specimen container which is used for diagnosis. While, some urine is tested right away using a dipstick, remaining is subjected to microscopic examination.
Here are some effective ways to stop the leakage of protein from kidneys. Know how to stop it and protect your health. It is important to understand that proteinuria is not a disease in itself, rather a symptom of an underlying disease.
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What Does The Test Result Mean
A negative test result means that there is no detectable amount of protein in the urine at the time of testing.
Protein detected in a random urine sample may be temporary due to an infection, medication, vigorous exercise, pregnancy, diet, cold exposure, or emotional or physical stress. Testing should be repeated after these conditions have resolved.
Protein in the urine can also be a warning sign of a serious condition and usually warrants further investigation. Typically, three positive urine samples over a period of time without other significant symptoms will often be followed up with additional tests, including a 24-hour urine.
Persistent and/or an increased amount of protein in the urine may indicate kidney damage or disease. With kidney disease, the amount of protein present is generally associated with the severity of the damage. Increasing amounts of protein over time indicate increasing damage and decreasing kidney function. The most common cause of protein in the urine is kidney damage resulting from:
- Diabetesproteinuria is one of the first signs of deteriorating kidney function in people with type 1 and 2 diabetes.
- High blood pressure proteinuria in someone with high blood pressure is also a first sign of declining kidney function.
Proteinuria may also be seen with many other diseases and conditions. A healthcare practitioner may order other tests and take into account those results to help determine the cause. Some examples of these causes include:
Protein In The Urine Is Not Just An Effect Of Ckd It Could Be A Cause
Now we know that proteinuria indicates damage to the kidney’s filter, and hence CKD. But if protein in the urine is just another downstream effect of kidney disease, then why do nephrologists make so much fuss about treating it?
Protein in the urine is not just another consequence of CKD, it directly makes kidney disease worse. It leads to further kidney damage, which leads to even more protein in the urine. It might start off as an effect, but it soon becomes the cause as well. Protein is not just a sign of the problem, it is the problem.
Let us look at the evidence to support the above conclusion. A lot of research has been done on this, and today, minimizing proteinuria is a valid “target” for retarding the progression of CKD.
A key factor in the progression of kidney disease is elevated pressure inside the kidney’s filter, the glomerulus. This is called intraglomerular hypertension. This leads to elevated filtration rate in the initial stages of kidney disease. Over the short term, this might help the kidney numbers “look pretty.” In the long run, it is actually maladaptive and GFR drops and is the reason for scar tissue formation is many kinds of CKD, e.g., diabetic kidney disease.
Protein in the urine makes intraglomerular hypertension worse. And so we have medical evidence that indicates that untreated proteinuria significantly increases the chances of your kidney disease progressing to failure .
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What Do My Test Results Mean
Test results may vary depending on your age, gender, health history, the method used for the test, and other things. Your test results may not mean you have a problem. Ask your healthcare provider what your test results mean for you.
Results are given in milligrams . Normal urine protein in adults is less than 150 mg within a 24-hour period.
What Are The Causes
There are no symptoms in the initial stages of glomerular proteinuria. In the later stages, there is a number of signs that help in the detection of the problem:
- Foamy urine
- Swelling of the hands, feet or abdomen
- Back pain and side pain
- Pain while urinating
- Hematuria or Blood in the urine
- Feeling sick all the time
- Shortness of breath
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How The Kidney Works
Inside each kidney, there are about one million nephrons. Each nephron is made up of a glomerulus , and a renal tubule.
- Each glomerulus acts like a sieve, helping to remove extra water and waste from the body, and holding on to blood cells and protein, which the body needs.
- Blood flows into the kidneys and to each glomerulus.
- Most of the water and some other substances in the blood pass through the glomeruli.
- This liquid flows into the renal tubule. Most of this liquid moves back into the bloodstream. The rest of it becomes urine.
- The urine leaves the kidney by the ureters and goes into the bladder, where it is stored until we are ready to go to the toilet.
Why Your Doctor May Test For High Protein In Urine
Proteinuria, or protein in the urine, occurs when your kidneys arent functioning normally, allowing protein to leave your body through your urine. Kidneys with normal function filter toxins out of the blood, while keeping nutrients like protein circulating. Having too much protein in your urine can mean that your kidneys are filtering too much protein out of your bloodprotein that your body needs to build muscles and maintain strong bones.
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About The Urinary System
The urinary system is made up of two kidneys, two ureters, a bladder and a urethra. The urinary system gets rid of things that the body no longer needs so that we can grow and stay healthy.
The kidneys are bean-shaped organs. They filter blood and remove extra water and waste in urine . Most of us have two kidneys. They are at the back on either side of our spine , near the bottom edge of our ribs.
The two ureters are long tubes that carry urine from the kidneys to the bladder.
The bladder is a muscular bag that stores urine until we are ready to urinate . It sits low down in the pelvis.
The urethra is a tube that carries urine from the bladder to the outside of the body. We urinate through the opening.