What Else Causes Protein In Urine
Proteinuria causes are linked to other conditions. Diabetes and high blood pressure are the two leading causes of chronic kidney disease , and kidney damage from those two conditions can result in proteinuria. Lupus, arthritis and other immune system disorders can also cause proteinuria. Protein in the urine can even be a warning sign of pre-eclampsia during pregnancy.
Why Your Doctor May Test For High Protein In Urine
Proteinuria, or protein in the urine, occurs when your kidneys arent functioning normally, allowing protein to leave your body through your urine. Kidneys with normal function filter toxins out of the blood, while keeping nutrients like protein circulating. Having too much protein in your urine can mean that your kidneys are filtering too much protein out of your bloodprotein that your body needs to build muscles and maintain strong bones.
How To Diagnose Abnormal Protein In Urine
People with high protein in urine, often dont know about the problem and live a normal life until the problem advances. With its advancement, one may experience some body indications that are
Earlier, no symptoms appear in protein loss in urine. When the problem advances, one may experience some body symptoms which are:
- Frequent urination
- Muscle cramping
- Puffiness around eyes, etc.
Based on your symptoms, your doctor can suspect you to have any kidney problem. In such a condition, your doctor suggests some laboratory tests to determine protein loss in in urine. The tests conducted are Urine tests, Blood tests, and another kidney functioning test .
Using these tests, your doctor can detect protein amount loss in urine and its cause. The whole treatment depends upon reports of the patient.
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How Does Protein Get Into Urine
Protein gets into the urine if the kidneys arent working properly. Normally, glomeruli, which are tiny loops of capillaries in the kidneys, filter waste products and excess water from the blood.
Glomeruli pass these substances, but not larger proteins and blood cells, into the urine. If smaller proteins sneak through the glomeruli, tubules recapture those proteins and keep them in the body.
However, if the glomeruli or tubules are damaged, if there is a problem with the reabsorption process of the proteins, or if there is an excessive protein load, the proteins will flow into the urine.
What Is This Test
This test measures the amount of protein in your urine.
Healthy kidneys usually filter protein out of the blood and absorb the protein. Then they send it back into the blood while waste material is passed out of your body as urine. But when your kidneys aren’t working the way they should, protein may pass into your urine. Protein in your urine is a condition called proteinuria, albuminuria, or microalbuminuria.
Many different chronic diseases, including kidney disease and diabetes, can cause protein in your urine. During pregnancy, protein in your urine can mean a very dangerous condition called preeclampsia, or extremely high blood pressure.
You may have this test after a dipstick urine protein test. That test needs only one urine sample that’s collected at your healthcare provider’s office.
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How The Test Is Performed
A 24-hour urine sample is needed:
- On day 1, urinate into the toilet when you get up in the morning.
- Afterward, collect all urine in a special container for the next 24 hours.
- On day 2, urinate into the container when you get up in the morning.
- Cap the container. Keep it in the refrigerator or a cool place during the collection period.
- Label the container with your name, the date, the time of completion, and return it as instructed.
For an infant, thoroughly wash the area around the urethra. Open a urine collection bag , and place it on the infant. For males, place the entire penis in the bag and attach the adhesive to the skin. For females, place the bag over the labia. Diaper as usual over the secured bag.
This procedure may take a couple of attempts. Active infants can move the bag, causing the urine to be absorbed by the diaper. The infant should be checked frequently and the bag changed after the infant has urinated into the bag. Drain the urine from the bag into the container provided by your health care provider.
Deliver it to the lab or your provider as soon as possible upon completion.
Protein In Urine Causes Symptoms & Treatments
When your kidneys are not working as well as they should, protein can leak through your kidneys filters and into your urine . Protein in your urine is called proteinuria or albuminuria. It is a sign that your kidneys are damaged.
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How Often Do I Need To Have A Test For Proteinuria
People who are at increased risk of developing kidney disease should have this test annually as a minimum or as part of their routine check-ups by the doctor. The exact frequency should depend on the clinical situation of the patient. It is important that people with CKD and diabetes should have a test for proteinuria as part of their regular reviews at least once a year.
Causes Of Protein In The Urine
Your kidneys, when working properly, filter waste products from your blood. They return protein and other materials that your body needs to function.
Some conditions and diseases can cause the level ofprotein in your urine to rise. Short term conditions that cause protein in the urine can include strenuous exercise, fever, heat or cold exposure and emotional distress. Long term conditions and diseases that can lead to protein in the urine include high blood pressure, kidney infection or disease, heart disease, diabetes, lupus and malaria.If a urine test reveals protein in your urine, your doctor may recommendfurther testing to determine the cause. Test may include a 24-hour urine collection to determine whether the protein in your urine is cause for concern. Your doctor may also follow up with an ultrasound or CT scan to look for issues like kidney stones or a biopsy to see what has caused damage to your kidneys.
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How Is This Test Done
This test needs a 24-hour urine sample. For this sample, you must collect all of your urine for 24 hours. Empty your bladder completely first in the morning without collecting it. Note the time. Then collect your urine every time you go to the bathroom over the next 24 hours. You will collect it in a container that your healthcare provider or the lab gives you.
Treatment For Proteinuria In Dogs
Proteinuria itself is not a condition, but it may indicate a more serious underlying health problem.
If your dog has proteinuria, your vet will first identify the underlying cause. This will likely involve additional tests, along with a detailed history of your dogs health and any changes in their behavior. They may also prescribe medications to prevent blood clots, such as a very low dose of aspirin or clopidogrel, a blood thinner.
Once the underlying cause has been discovered, your vet can develop a treatment plan. Some of the conditions and related treatments that are linked to proteinuria include:
How To Reduce Protein In Urine Naturally
Protein is known to be the primary compound found in the body cells. It is a component of food that is found in most parts of the body. It is considered to be the building block of the body. Everything in our body except for the skeletal system is protein therefore, the bodys existence is at stake in lack of protein. Kidneys when they get damaged, do not perform their function of filtration that leads to loss of protein in the urine.
Kidneys play a vital role in cleansing the body organs and removing toxins from the blood. When kidneys lose their ability to function efficiently due to acute kidney disease, chronic kidney failure, or any kidney infection, they start expelling out nutrients from the body which results in the deficiency of the nutrient creating other medical problems.
Control Your Blood Sugar
Diabetes is one of the biggest cause for kidney diseases. If you control or reverse your diabetes you can prevents lots of health problems.
If blood sugar begins to increase then you have diabetes.controlling blood sugar naturally or through medication or combination of both whatever works has to be followed to ensure that diabetes doesn’t increase.
Diet control, exercise and regular monitoring of blood sugar will go a long in getting rid of proteins in urine.
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How Is Proteinuria Treated
Treatment depends on the underlying condition that caused proteinuria. Each condition requires different treatments.
If kidney disease is confirmed, a treatment plan might include medication, diet changes, weight loss and exercise. Diabetes and hypertension patients with proteinuria might need blood pressure medication, and those with diabetes will have to control their blood sugar. Diabetes patients should receive glomerular filtration rate blood tests every year and may be referred to a nephrologist, a doctor who specializes in the kidneys.
Pregnant women with preeclampsia should be watched carefully. The condition, although serious during pregnancy, usually resolves itself once the baby is born. Proteinuria patients with low blood pressure should schedule annual urine tests and blood pressure checks.
If proteinuria isnt accompanied by diabetes, high blood pressure or any other medical condition, blood pressure medication still might be prescribed to prevent kidney damage. Blood pressure and urine should be checked every six months to make sure kidney disease isnt present. As for those with mild or temporary proteinuria, treatment may not be necessary.
If I Have A Positive Urine Protein Test What Other Tests Might Be Done In Follow Up
A positive urine protein test tells your healthcare practitioner that protein is present in your urine, but it does not indicate which types are present or the cause of the proteinuria. When investigating the reason, your health care practitioner may order additional laboratory tests, such as:
- Comprehensive metabolic panel includes tests such as BUN, creatinine, albumin and total protein, which help evaluate kidney and liver function
- A full urinalysisif a condition such as urinary tract infection is also suspected
- Serum and urine protein electrophoresis testto determine which proteins are being released into the urine and in what quantities this is especially true if your health care practitioner suspects abnormal monoclonal protein production, such as with multiple myeloma or lymphoma.
If kidney disease or damage is suspected, your healthcare practitioner may also order imaging scans to evaluate the appearance of your kidneys.
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Getting Rid Of Strong Urine Odor
To get rid of smelly urine that has a strong, ammonia-like odor, you may want to try one or more of the following tips.
Stay hydrated: Drinking water more often can help dilute your urine and reduce any odor attributed to it.
Reduce protein intake: Eating less protein can reduce your bodys production of urea and as a result get rid of that nasty odor.
Urinate more often: While its not always possible, urinating whenever you feel the urge rather than waiting for your bladder to fill can reduce the odor of your urine, as it spends less time being held in the bladder and is less concentrated.
Ask about your medication:Some medications can cause odorous urine as a side effect, so if you begin experiencing this after starting a new medication, mention it to your doctor. They may need to switch your medication or dosage.
Keep track of other symptoms: While strong-smelling urine alone may not be a serious condition, when it is present along with other more worrying symptoms, it could be indicative of issues with your kidneys, bladder, or even a sexually transmitted infection.
Clean yourself thoroughly: Personal hygiene is always important, especially of the genital area. If you are not cleaning yourself thoroughly or frequently enough, the buildup of bacteria and remnants of urine can cause a strong, unpleasant scent both when you are urinating and when you are not, as the scent can linger in your undergarments and on your skin.
Factors That Lead To Protein In The Urine
Excess protein loss in the urine is termed as proteinuria. There are various reasons that lead to the condition of proteinuria, these include:
- Diabetes is a major cause of proteinuria. Glycosuria is an increased blood sugar level damage the filters of the kidneys that leads to decreased functioning of the kidneys resulting in excess loss of protein in the urine.
- Hypertension: People with high blood pressure have a higher tendency to develop the condition of proteinuria.
- Overweight and obese: Obesity and overweight are responsible for multiple problems in the body. This factor also increases the vulnerability of proteinuria.
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What Causes Kidneys To Leak Protein & How To Stop It
Does your urine appear frothy or slimy? It could be proteinuria. This occurs when kidneys are unable to filter protein, which then leaks out in the urine. Know what causes kidneys to leak protein and how to stop it.
Leakage of protein in urine via kidneys can not only change the appearance of urine but can also suggest presence of some chronic kidney disorder. Instead of ignoring it for long, get medical advice as early as possible to prevent worsening of the symptoms. But, before you visit the doctor, do understand about proteinuria and what can be done to cure it! Let us understand what causes kidneys to leak protein and ways to stop it.
Urine Protein: Creatinine Ratio
The urine protein:creatinine ratio has become the preferred method for the quantification of proteinuria in the non-pregnant population, due to high accuracy, reproducibility, and convenience when compared to timed urine collection. The PC ratio is highly correlated with proteinuria by 24-hour urine collection in pregnant women, as it is in patients with CKD. Most studies evaluating the accuracy of the PC ratio in pregnancy have focused on women with hypertensive pregnancy undergoing evaluation for pre-eclampsia. A systematic review, which included 2790 women from 15 studies, concluded that a PC ratio less than 0.13 mg protein/mg creatinine has good sensitivity for excluding proteinuria in hypertensive pregnancy.36
There are no data validating the use of the PC ratio to follow changes in urinary protein excretion in pregnant patients with CKD, but based on strong data supporting its use in the non-pregnant population, we recommend its use in pregnancy for this purpose.
Hilary S. Gammill, Arun Jeyabalan, in, 2019
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How Is A Urine Test Done
A simple urine test can be done in your doctor’s office. You will be asked to pee into a clean cup called a specimen cup. Only a small amount of your urine is needed to do the test. Some of the urine is tested right away with a dipstick a thin, plastic strip that is placed in the urine. The rest is examined under a microscope.
How Is The Test Used
Urine protein testing is used to detect excess protein in the urine . A semi-quantitative test such as a dipstick urine protein may be used to screen for the presence of protein in the urine as part of a routine urinalysis.
A urine protein test may be used to screen for, help evaluate, and monitor kidney function and to help detect and diagnose early kidney damage and/or disease. However, the test can also help screen for several other conditions that can cause proteinuria.
If slight to moderate amounts of protein are detected, then a repeat urinalysis and dipstick protein may be performed at a later time to see if there is still protein in the urine or if it has become undetectable.
If there is a large amount of protein in the first sample, repeat testing will be ordered. If increased levels of urine protein are observed in follow-up specimens, then a 24-hour urine protein may be ordered along with certain blood tests. Since the dipstick method primarily measures the protein albumin, and if follow-up, repeat urine samples are positive, a 24-hour urine test also may be ordered to obtain more detailed information.
Either a 24-hour urine protein or a random protein to creatinine ratio may be used to monitor a person with known kidney disease or damage. A dipstick urine protein and/or a protein to creatinine ratio may be used to screen people on a regular basis when they are taking a medication that may affect their kidney function.
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What Does The Test Result Mean
A negative test result means that there is no detectable amount of protein in the urine at the time of testing.
Protein detected in a random urine sample may be temporary due to an infection, medication, vigorous exercise, pregnancy, diet, cold exposure, or emotional or physical stress. Testing should be repeated after these conditions have resolved.
Protein in the urine can also be a warning sign of a serious condition and usually warrants further investigation. Typically, three positive urine samples over a period of time without other significant symptoms will often be followed up with additional tests, including a 24-hour urine.
Persistent and/or an increased amount of protein in the urine may indicate kidney damage or disease. With kidney disease, the amount of protein present is generally associated with the severity of the damage. Increasing amounts of protein over time indicate increasing damage and decreasing kidney function. The most common cause of protein in the urine is kidney damage resulting from:
- Diabetes proteinuria is one of the first signs of deteriorating kidney function in people with type 1 and 2 diabetes.
- High blood pressure proteinuria in someone with high blood pressure is also a first sign of declining kidney function.
Proteinuria may also be seen with many other diseases and conditions. A healthcare practitioner may order other tests and take into account those results to help determine the cause. Some examples of these causes include: