What Happens During A Protein In Urine Test
A protein in urine test can be done in the home as well as in a lab. If in a lab, you will receive instructions to provide a “clean catch” sample. The clean catch method includes the following steps:
If at home, you will use a test kit. The kit will include a package of strips for testing and instructions on how to provide a clean catch sample. Talk to your health care provider if you have any questions.
Your health care provider may also request you collect all your urine during a 24-hour period. This “24-hour urine sample test” is used because the amounts of substances in urine, including protein, can vary throughout the day. Collecting several samples in a day may provide a more accurate picture of your urine content.
Hypertension And Protein In Urine
Hypertension is the most common cause of kidney disease and protein in urine after Diabetes mellitus. The key to preventing hypertension related complications is to diagnose hypertension early and treat it before it has been present long enough to cause chronic disease. Hypertension may be discovered years after it starts but treating hypertension even if found late has a lower chance of reversing kidney disease, but will prevent worsening of kidney disease.
How Do I Do A 24
In children who are potty-trained, you should start the collection on a day when your child doesn’t go to school, usually on a Sunday. As soon as your child gets out of bed in the morning, have him or her urinate into the toilet. This urine is not saved just flush it down the toilet. Write down the exact time your child urinates.
After this, whenever your child needs to urinate, have your child urinate in the special container the doctor or the laboratory gives you. For girls, collect the urine first in a urine hat, then pour it into the special container. You don’t need to mark the times when these urine samples are collected.
It’s important to collect all the urine your child produces all day and in the night. The next morning, wake your child up at about the same time as you did the day before. Have your child urinate into the container one last time. This ends the 24-hour collection. Now write the date and the time on the container label. Bring the container to the laboratory on this day. Since bacteria can grow in urine at room temperature, it’s important to keep the urine container in a refrigerator during the collection and before you deliver it to the laboratory. Be sure to wash your hands after handling the container.
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Who Should Have Their Urine Routinely Tested For Proteinuria
NICE has suggested that the following people should be considered for a urine test for proteinuria:
- People with kidney function known to be less than 65% of normal. This assessment is made using a blood test for your kidney measurement, called your estimated glomerular filtration rate .
- People with diabetes.
- People with heart and blood vessel disease .
- People with complex diseases which may involve the kidneys for example, systemic lupus erythematosus or myeloma.
- People with a family history of kidney failure or a family history of inherited kidney disease.
- People found to have blood in their urine.
What Is Pediatric Proteinuria
Proteinuria is an excess if protein in your child’s urine. If your child has proteinuria, its often not serious. But sometimes, it can indicate a more serious problem with the kidneys. You should watch for any signs that your childs fluids seem out of balance and check with a doctor.
If proteinuria indicates a kidney disease, your doctor will refer your child to a nephrologist, a doctor who specializes in treating kidney diseases.
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How To Diagnose Abnormal Protein In Urine
People with high protein in urine, often dont know about the problem and live a normal life until the problem advances. With its advancement, one may experience some body indications that are
Earlier, no symptoms appear in protein loss in urine. When the problem advances, one may experience some body symptoms which are:
- Frequent urination
- Muscle cramping
- Puffiness around eyes, etc.
Based on your symptoms, your doctor can suspect you to have any kidney problem. In such a condition, your doctor suggests some laboratory tests to determine protein loss in in urine. The tests conducted are Urine tests, Blood tests, and another kidney functioning test .
Using these tests, your doctor can detect protein amount loss in urine and its cause. The whole treatment depends upon reports of the patient.
Factors That Lead To Protein In The Urine
Excess protein loss in the urine is termed as proteinuria. There are various reasons that lead to the condition of proteinuria, these include:
- Diabetes is a major cause of proteinuria. Glycosuria is an increased blood sugar level damage the filters of the kidneys that leads to decreased functioning of the kidneys resulting in excess loss of protein in the urine.
- Hypertension: People with high blood pressure have a higher tendency to develop the condition of proteinuria.
- Overweight and obese: Obesity and overweight are responsible for multiple problems in the body. This factor also increases the vulnerability of proteinuria.
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Can I Get Nephrotic Syndrome Even After I Have A Transplant
Yes, you can get nephrotic syndrome even after your transplant. Remember, nephrotic syndrome is not a single disease. It is caused by different diseases that affect your kidneys. If you get a kidney transplant but do not treat the disease that is affecting your kidneys, the disease may continue to harm your new kidney.
Who Should Be Tested For Protein In The Urine
If you are part of a group that is considered high risk for kidney disease, your doctor will test your urine for protein as part of your regular preventative care. People who are at risk for kidney disease include:
- Those who are 65 or older.
- Those who have a family history of kidney disease.
- Those who have high blood pressure or diabetes.
- Members of certain ethnic groups, including Hispanics, Native Americans, Asians and African Americans.
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What Is Orthostatic Proteinuria
Orthostatic proteinuria occurs in some older children and teenagers. The word orthostatic means upright. The condition is called orthostatic proteinuria because protein goes into the urine only when the child is in the upright position .
Children with this condition have no kidney damage but, for some unknown reason, they lose protein into the urine during the day when they are active. At night, while they sleep, their kidneys don’t let any protein into the urine. Your doctor diagnoses this harmless condition by checking two urine samples. The first one is collected in the morning, right after your child gets up, and it’s kept in one container. The second sample is collected during the day . If your child has orthostatic proteinuria, the morning sample won’t have protein in it. The urine collected during the day will have protein in it.
How Do Doctors Test For Nephrotic Syndrome
Healthy kidneys remove extra fluid and waste from your blood but let proteins and other important nutrients pass through and return to your blood stream. The only way to know how well your kidneys are working is to get tested. Tests doctors use for kidneys are:
To be sure you do not have a problem with your kidneys, you should have both, a urine and a blood test. Having a urine and a blood test is important because you could have normal blood test results, but you could still have too much protein in your urine. Protein in your urine could mean you have kidney disease.
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Protein In The Urine Is Not Just An Effect Of Ckd It Could Be A Cause
Now we know that proteinuria indicates damage to the kidney’s filter, and hence CKD. But if protein in the urine is just another downstream effect of kidney disease, then why do nephrologists make so much fuss about treating it?
Protein in the urine is not just another consequence of CKD, it directly makes kidney disease worse. It leads to further kidney damage, which leads to even more protein in the urine. It might start off as an effect, but it soon becomes the cause as well. Protein is not just a sign of the problem, it is the problem.
Let us look at the evidence to support the above conclusion. A lot of research has been done on this, and today, minimizing proteinuria is a valid “target” for retarding the progression of CKD.
A key factor in the progression of kidney disease is elevated pressure inside the kidney’s filter, the glomerulus. This is called intraglomerular hypertension. This leads to elevated filtration rate in the initial stages of kidney disease. Over the short term, this might help the kidney numbers “look pretty.” In the long run, it is actually maladaptive and GFR drops and is the reason for scar tissue formation is many kinds of CKD, e.g., diabetic kidney disease.
Protein in the urine makes intraglomerular hypertension worse. And so we have medical evidence that indicates that untreated proteinuria significantly increases the chances of your kidney disease progressing to failure .
What Is This Test
This test measures the amount of protein in your urine.
Healthy kidneys usually filter protein out of the blood and absorb the protein. Then they send it back into the blood while waste material is passed out of your body as urine. But when your kidneys aren’t working the way they should, protein may pass into your urine. Protein in your urine is a condition called proteinuria, albuminuria, or microalbuminuria.
Many different chronic diseases, including kidney disease and diabetes, can cause protein in your urine. During pregnancy, protein in your urine can mean a very dangerous condition called preeclampsia, or extremely high blood pressure.
You may have this test after a dipstick urine protein test. That test needs only one urine sample that’s collected at your healthcare provider’s office.
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What Causes Nephrotic Syndrome
Nephrotic syndrome happens when you have a disease that damages the filters in your kidneys causes them to not work as they should. There are primary and secondary causes of nephrotic syndrome.
Primary causes of nephrotic syndrome are diseases that affect only the kidneys.
The most common primary cause of nephrotic syndrome in adults is a disease called focal segmental glomerulosclerosis . The only way to know for sure whether you have FSGS is to get a kidney biopsy. Even when treated, most people with FSGS will eventually develop kidney failure and will need to start dialysis or have a kidney transplant to live. After transplant, there is still a chance that FSGS will return and you may lose your new kidney.
In children, the most common primary cause of nephrotic syndrome is minimal change disease.
Secondary causes of nephrotic syndrome are diseases that affect the whole body, including the kidneys.
Most of the time, nephrotic syndrome happens because of secondary causes. The most common secondary cause of nephrotic syndrome in adults is diabetes.
The most common secondary cause of nephrotic syndrome in children is diabetes.
Abnormally High Level Of Protein In The Urine Could Indicate Kidney Disease
Proteinuria could indicate CKD. Where does protein in the urine come from? The protein is there in the blood. It exists as different types . Your muscles are primarily made of protein. The antibodies that circulate in your system fighting infection are protein. Hence protein is essential, but you normally shouldn’t be peeing it out into the urine.
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Causes Of Protein In The Urine
Your kidneys, when working properly, filter waste products from your blood. They return protein and other materials that your body needs to function.
Some conditions and diseases can cause the level ofprotein in your urine to rise. Short term conditions that cause protein in the urine can include strenuous exercise, fever, heat or cold exposure and emotional distress. Long term conditions and diseases that can lead to protein in the urine include high blood pressure, kidney infection or disease, heart disease, diabetes, lupus and malaria.If a urine test reveals protein in your urine, your doctor may recommendfurther testing to determine the cause. Test may include a 24-hour urine collection to determine whether the protein in your urine is cause for concern. Your doctor may also follow up with an ultrasound or CT scan to look for issues like kidney stones or a biopsy to see what has caused damage to your kidneys.
How Is Pediatric Proteinuria Diagnosed
If you or your childs pediatrician suspect that your child has proteinuria, a condition in which protein leaks from the blood into the urine, the doctor will recommend a urine test.
In the past, a 24-hour urine collection was required to diagnose proteinuria. The patient would collect urine in a single container from the first visit to the bathroom in the morning through the first visit on the next day. This test may still be used, but most of the time, a simple urine test can be done in a doctors office to test how much protein is in your childs urine. A chemically-treated paper dipped into the urine sample will change color if protein levels are high.
If your child has no symptoms and a urine sample collected first thing in the morning indicates no protein or only trace amounts, the doctor may suggest that your child be tested again in a year. If protein is discovered in the urine, another first morning sample should be tested and also examined under a microscope, and further urinalysis the physical, chemical, and microscopic testing of a sample of urinewill be necessary. If the urine tests reveal excess protein and urinalysis results are abnormal, your child may need further evaluation because if the proteinuria persists, it can mean that your childs kidney function is declining.
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How Does Protein Get Into Urine
Protein gets into the urine if the kidneys arent working properly. Normally, glomeruli, which are tiny loops of capillaries in the kidneys, filter waste products and excess water from the blood.
Glomeruli pass these substances, but not larger proteins and blood cells, into the urine. If smaller proteins sneak through the glomeruli, tubules recapture those proteins and keep them in the body.
However, if the glomeruli or tubules are damaged, if there is a problem with the reabsorption process of the proteins, or if there is an excessive protein load, the proteins will flow into the urine.
What Do My Test Results Mean
Test results may vary depending on your age, gender, health history, the method used for the test, and other things. Your test results may not mean you have a problem. Ask your healthcare provider what your test results mean for you.
Results are given in milligrams . Normal urine protein in adults is less than 150 mg within a 24-hour period.
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Change Your Protein Intake
Just because there are high protein levels in urine you dont have to give up proteins all together.
However, lowering the consumption of proteins and changing to Healthy of proteins will make a significant improvement in your urine proteins.
Avoid red meats and move to lean proteins like chicken meat. Eat more fishes and soy proteins.
Soy proteins are light on kidneys as compared to animal proteins.
Since high blood pressure and diabetes are the main causes of rise if proteins in urine, fix these and you will get rid of proteinuria. Take following precautions.
- Lead a healthy life by exercising and sleeping well
- Reduce stress by deep breathing and meditation
- Drink lots of water throughout the day
- Avoid refined carbohydrates and sugar
- Stop alcohol and sugary colas and sodas
You are lucky if you identify proteins in urine early and take preventative action. Urine test every year if you are above 60 can save you from.kidney disease.
What Causes Protein In The Urine
Healthy kidneys remove extra fluid and waste from your blood and transform it into urine. Healthy kidneys do not remove proteins and other important nutrients, which pass through and return to your blood. But when your kidneys are damaged, they may let this protein leak into your urine. This causes high levels of protein in your urine. Anyone can have protein in their urine. You may be more likely to have protein in your urine if you have one or more of the risk factors for kidney disease. There are health problems that can cause long-lasting protein in the urine, and some that can cause short-term protein in the urine.
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